Questions, answered

Primaderm was founded by Dr. José María García Antón, a chemist with more than 35 years of research into active molecules. In 2002, Argireline® was born in his lab, today one of the most famous peptides in skincare. His idea is simple: skincare should be built on science, and it should be honest.

It means every active ingredient has a clear job. Primaderm designs smart, skin-friendly molecules, many inspired by the skin’s own structure, so each formula does exactly what it promises, with care you can see and feel.

Argireline® (Acetyl Hexapeptide-8) is the peptide that changed how the world thinks about expression lines. It helps reduce the appearance of wrinkles and expression lines, especially on the forehead and around the eyes. You’ll find it across the Xpert Expression range.

Start with Xpert Expression Serum Sublime™: light, fast-absorbing, for face, neck and neckline. Add the Xpert Expression Cream for your skin type, and the Contour Eye Gel for the eye area.

Xpert Expression Cream Combination / Oily: the same peptide care in a lighter texture.

Begin with the Biodefense range. With Aeonome™, a prebiotic that helps keep the skin’s environment balanced, Biodefense helps your skin feel calm, comfortable and hydrated. Dermatologically tested on sensitive skin and fragrance-free.

Both give SPF 50+ broad-spectrum UVA/UVB protection with encapsulated filters, for all skin types. Urban Advanced adds Marsturizer™ for extra hydration and moisture-barrier support, and helps reduce the visible signs of premature skin ageing caused by the sun. It’s our pick if you spend time outdoors, in Light (mattifying) and Rich (moisturizing) textures.

Urban Advanced · LightMattifying · RM 190Urban Advanced · RichMoisturizing · RM 190

Take our 30-second quiz.

Morning: cleanser → serum → cream → sunscreen. Evening: cleanser → serum → cream or mask. Adding several new products? Introduce them one at a time and enjoy getting to know each one.

Two steps for a truly clean feel. First, Deep Cleansing Oil-to-Milk melts away makeup, sunscreen and excess oil. Then Balance Cleansing Gel removes sweat and daily impurities, leaving skin soft and comfortable.

For blemish-prone skin, every day. For dry or sensitive skin, 1–2 times a week. Massage onto damp skin for 30 seconds (avoid the eye area), leave on for 1 minute, then rinse.

Whenever you want an intensive two-week boost: before a special occasion, or to give your routine a lift. Use one vial per week for two weeks, morning and evening, on the areas with visible lines. It helps reduce the appearance of wrinkles and expression lines and leaves skin looking brighter and more refreshed.

Apply a generous layer to clean, dry skin on the face and neck. Leave for 2–3 minutes, then massage gently until absorbed, and leave on overnight. Use 2–3 times a week.

We always recommend checking new skincare with your doctor during this special time. We’re happy to send you the full ingredient list to share with them. Just message us.

Tell us which product and we’ll check the full ingredient list (INCI) for you. Every product page also lists the full ingredients.

Send us the ingredient name and the product you’re interested in, and we’ll check the full ingredient list for you right away.