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AFFILIATE

Primaderm signature active · Marine biotech extract

Pauseîle™

The extract that rebuilds the mortar between your skin cells.

Pauseîle™ helps the skin's surface seal itself the way healthy skin does, so water stays in, irritants stay out, and skin feels soft and supple for longer.

HydrationBarrierLess water lossSoft, supple skin
Biodefense Prebiotic Cream being scooped from the jar

In one minute

What it is

A biotechnological extract of marine origin, produced in the laboratory. Used at 2% in both Biodefense creams and the mask.

What it does

It supports the skin's own moisture barrier, the "mortar" between the surface cells, so the skin holds water for longer and feels comfortable between applications.

Why it matters

Adding moisturiser only works while it sits on the skin. A barrier that makes its own mortar stays hydrated between applications, even in air-conditioning.

Diagram of the outer skin as bricks (corneocytes) held together by lipid mortar
The outer skin is built like a wall: cells are the bricks, lipids and ceramides are the mortar.

The idea, simply

Think of your skin's surface as a tiled wall.

The cells are the tiles. Between them sits the grout: ceramides, fatty acids and cholesterol. When the grout crumbles, water leaks out and irritants seep in, and the skin feels tight, rough and reactive.

Pauseîle™ helps the skin keep its grout in good condition. Instead of only painting moisture on top, it supports the seal, so the water your skin already has stays where it belongs.

Fix the grout, and the wall holds water on its own.

Rich white swirl of Biodefense Prebiotic Cream texture
Delivered in a cream that feels comfortable on both dry and combination skin.

A little science, made simple

Hydration from the first hour, still there at day 28.

Primaderm measured hydration and water loss on volunteers over four weeks.

1 hourHydration already up, and sustained for 28 days
7 daysWater loss through the skin down 40%
6 daysThe skin's own barrier lipids up 39%

What the studies show

Water in, water kept.

+39%
Hydration
from 1 hour, sustained to day 28
−40%
Water loss (TEWL)
after 7 days at 2%
+39%
Skin's own barrier lipids
after 6 days at 1%

Ingredient studies as reported in Primaderm's technical documentation (in vivo and in vitro); not tests of the finished product. Cosmetic effect on the look and feel of the skin; individual results vary.

Who it's for

If your skin feels tight an hour after moisturising.

  • Dehydrated skin in air-conditioned offices and cars
  • Skin that feels rough or looks flaky despite creams
  • Combination skin that is oily yet still tight
  • Skin recovering from over-cleansing or strong actives
Hand holding a jar of Biodefense Prebiotic Cream
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